ESBS Bioinformatics Practical Sessions

Here you will find all the materials needed for your bioinformatics practical sessions (TDs) at ESBS.

In addition to the exercise sheets, the site also provides useful resources such as guides and links to external courses that will help you become familiar with the tools and concepts you will need.

Practical sessions

1A - Introduction to Bioinformatics

Here are the practicals for first-year students. They cover fundamental concepts and essential tools in bioinformatics with an introduction to the command line interface (CLI):

• 1 - Database exploration
• 2 - Functional analysis of a gene list and sequence comparison
• 3 - Similarity searches
• 4 - Analysis of protein families
• 5 - Multiple alignment and molecular phylogeny

2A - Genomics and Epigenomics

The Genomics and Epigenomics practicals are aimed at second-year students. They will guide you through several analyses commonly used in genomics:

• 1 - Pre-processing of sequencing reads
• 2 - Read mapping on a reference genome
• 3 - De novo assembly
• 4 - Annotation of a complete prokaryotic genome
• 5 - Analysis of eukaryotic sequences

3A - Comparative and Medical Genomics

These advanced practicals are intended for third-year students:

• 2 - Exome analysis
• 3 - Personal genomics: variants

Pharma - Introduction to Bioinformatics

These practicals for fifth-year pharmacy students introduce some of the bioinformatics tools and techniques needed in pharmaceutical

• 1 - Pre-processing of sequencing reads
• 2 - Database exploration
• 3 - Functional analysis of a gene list and sequence comparison
• 4 - Similarity searches
• 5 - Analysis of Protein Families

Help and Support

If you need additional guidance, visit our Help section where you’ll find detailed resources to assist you with the technical aspects of the practicals, as well as external links to bioinformatics courses:

• Galaxy Help: Get familiar with the Galaxy platform, a popular tool for conducting bioinformatics analyses without extensive programming knowledge.
• Server Connection Guide: Step-by-step instructions to connect to the server used in the practical sessions.

Additionally, you will find links to other existing bioinformatics courses and external resources to enhance your learning experience.

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We hope these practicals and resources will guide you in your bioinformatics journey, helping you develop the skills and knowledge needed for your academic and research projects.